5-Methoxy-2-tetralone CAS#32940-15-1
High-Value Pharmaceutical Intermediate: Widely used in pharmaceutical R&D, particularly in the synthesis of sertraline analogues and other neurotransmitter-related compounds.
Versatile Chemical Reactivity: The substituted tetralone structure enables diverse functional modifications, supporting a broad range of synthetic applications.
Reliable Physicochemical Properties: Stable molecular structure (C₁₁H₁₂O₂) with consistent melting point (32–36 °C) ensures predictable performance in laboratory processes.
Distinct Physical Form for Easy Handling: Yellow to orange solid appearance allows for straightforward identification and convenient handling during production and research.
5-Methoxy-2-tetralone Chemical Properties
| Melting point | 32-36 °C (lit.) |
| Boiling point | 165°C/10mmHg(lit.) |
| density | 1.124±0.06 g/cm3(Predicted) |
| vapor pressure | 0.059Pa at 25℃ |
| Fp | >230 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Chloroform, Dichloromethane, Ethyl Acetate, Methanol |
| form | Solid |
| color | Yellowish Orange |
| BRN | 1451623 |
| InChIKey | MDAIAXRTLTVEOU-UHFFFAOYSA-N |
| LogP | 1.8 at 25℃ |
| CAS DataBase Reference | 32940-15-1(CAS DataBase Reference) |
| Hazard Codes | Xn |
| Risk Statements | 20/21/22-36/37/38 |
| Safety Statements | 26-36-24/25 |
| WGK Germany | 3 |
| HS Code | 29145090 |
5-Methoxy-2-tetralone is a core building block in the synthesis of a variety of bioactive molecules:
Pharmaceutical Synthesis: It is a key intermediate in the synthesis of rotigotine, a dopamine receptor agonist used to treat Parkinson's disease and restless legs syndrome.
Research and Development Applications: Widely used in laboratory-scale synthetic research as a starting material for constructing polycyclic aromatic hydrocarbons and functionalized naphthalene derivatives.
