L-Isoleucine CAS#73-32-5
Versatile Solubility – Soluble in water, diluted mineral acids, and alkaline solutions, allowing flexibility in various formulations.
Distinct Physical Properties – Exhibits a sharp sublimation point (168–170°C) and decomposes at around 284°C, supporting controlled processing and handling.
Stable pH Range – A 1% solution maintains a pH between 5.5 and 7.0, making it suitable for applications requiring mild acidity or near-neutral conditions.
High-Yield Absolute – The absolute, obtained via alcoholic extraction of the concrete, provides a semisolid product with characteristic aroma and good extraction yield (55–60%).
Crystalline leaflets or a white crystalline powder with a bitter taste. It is soluble in 25 parts of water, slightly soluble in hot alcohol, and soluble in diluted mineral acids and alkaline solutions. It sublimes at 168–170°C and melts with decomposition at approximately 284°C. The pH of a 1% solution ranges from 5.5 to 7.0. The absolute is obtained by alcoholic extraction of the concrete with yields of about 55–60%, resulting in a semisolid, olive-green mass with a characteristic ambergris aroma.
L-Isoleucine Chemical Properties
Melting point | 288 °C (dec.) (lit.) |
Alpha | 41 º (c=4, 6N HCl) |
Boiling point | 225.8±23.0 °C(Predicted) |
Bulk density | 470kg/m3 |
Density | 1.2930 (estimate) |
FEMA | 4675 | L-ISOLEUCINE |
Refractive index | 40.5 ° (C=4, 6mol/L HCl) |
Fp | 168-170°C |
Storage temp | Store below +30°C |
Solubility | 1 M HCl: 50 mg/mL |
Form | powder |
Pka | 2.32, 9.76(at 25℃) |
Color | White to Off-white |
Odor | odorless |
PH | 5.5-6.5 (40g/l, H2O, 20℃) |
Biological source | synthetic |
Optical Rotation | [α]20/D +41.0±1°, c = 5% in 6 M HCl |
Water Solubility | 41.2 g/L (50 ºC) |
λmax | λ: 260 nm Amax: 0.07 |
JECFA Number | 2118 |
Merck | 14,5179 |
Sublimation | 168-170 ºC |
BRN | 1721792 |
InChIKey | AGPKZVBTJJNPAG-WHFBIAKZSA-N |
LogP | 0.80 |
CAS DataBase Reference | 73-32-5(CAS DataBase Reference) |
NIST Chemistry Reference | Isoleucine(73-32-5) |
EPA Substance Registry System | L-Isoleucine (73-32-5) |
Safety Information
Hazard Codes | Xn |
Risk Statements | 40 |
Safety Statements | 24/25-36-22 |
WGK Germany | 3 |
RTECS | NR4705000 |
TSCA | Yes |
HS Code | 29224995 |
Hazardous Substances Data | 73-32-5(Hazardous Substances Data) |
Toxicity | LD50 intraperitoneal in rat: 6822mg/kg |
L-Isoleucine, also called Isoleucine, is an amino acid and an isomer of leucine. It plays a key role in hemoglobin synthesis and in regulating blood sugar and energy levels. As an essential amino acid that cannot be synthesized by the body, L-Isoleucine supports endurance and aids in muscle repair and rebuilding. It is particularly valuable for bodybuilders, as it helps increase energy and promotes recovery after training.
