Puerarin CAS#3681-99-0
Nutritional and Medicinal Value: Puerarin is a flavonoid glycoside derived from Pueraria alba or Pueraria thomsonii, recognized for its significant health benefits and long history of use in traditional medicine.
Rich in Active Compounds: As one of the key active compounds in Pueraria lobata, puerarin contributes to the plant’s renowned therapeutic properties.
Versatile Applications: Puerarin has gained increasing attention in food and medicine, showcasing its broad utility in both sectors.
Cultural Significance: Often called the "south ginseng" of China, puerarin holds strong cultural and historical value, making it a trusted remedy in traditional Chinese medicine.
Puerarin, also referred to as pueraria flavonoids, is a flavonoid glycoside derived from the roots of Pueraria alba or Pueraria thomsonii and is one of the key active compounds in Pueraria lobata. Known for its significant nutritional and medicinal value, pueraria has long been revered as the "south ginseng" of China. In recent years, puerarin has gained increasing attention in China for its applications in both food and medicine.
Parameters
Melting point | 187-189°C |
Boiling point | 688.0±55.0 °C(Predicted) |
density | 1.614±0.06 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility | DMSO (Slightly), Methanol (Slightly) |
form | |
pka | 6.46±0.20(Predicted) |
color | White to Off-white |
Water Solubility | Soluble in DMSO or DMF. Slightly soluble in water or ethanol |
λmax | 303nm(MeOH)(lit.) |
BRN | 64198 |
InChIKey | HKEAFJYKMMKDOR-NCHCSYJDSA-N |
SMILES | OC1=CC=C2C(C(C3C=CC(O)=CC=3)=COC2=C1[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)=O |&1:18,19,20,22,24,r| |
LogP | 0.408 (est) |
CAS DataBase Reference | 3681-99-0(CAS DataBase Reference) |
Safety Information
Hazard Codes | F,C |
Risk Statements | 11-34 |
Safety Statements | 22-24/25-45-36/37/39-26-16 |
WGK Germany | 3 |
RTECS | UO5216000 |
F | 10 |
HS Code | 29389090 |
Puerarin is a natural isoflavone extracted from plants of the Pueraria genus, commonly used in traditional Chinese herbal medicine. It is metabolized by intestinal bacteria into the phytoestrogens daidzein and equol, contributing to antithrombotic, antiallergic, and other health benefits. When administered intraperitoneally, puerarin induces various responses by modulating serotonin receptors. Additionally, at concentrations of 20-40 μM, it inhibits lipopolysaccharide-induced activation of NF-κB in RAW 264.6 macrophages.
