Ginsenoside Rb1 CAS#41753-43-9
Anti-Aging Benefits: Ginsenoside Rb1 is recognized for its anti-aging properties, proven in both animal models and cell cultures.
Active Ingredient: It is the primary active component in American ginseng, with ginsenoside Rb1 being crucial for its therapeutic effects.
Cell Regeneration: The compound enhances HAS2 expression by activating ERK and AKT pathways, supporting skin cell regeneration and health.
Natural Source: Derived from Panax ginseng, ginsenoside Rb1 offers a natural solution for promoting health and longevity.
Ginsenoside Rb1, a glycosylated PPD-type ginsenoside, features two sugar molecules attached to C-3 and two to C-20. It is considered the primary active component in American ginseng. Research has highlighted the anti-aging properties of ginsenoside Rb1, observed in both animal models and cell cultures.
The key compound in ginsenoside Rb1, 20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol (20GPPD), has been shown to enhance HAS2 expression by activating ERK and AKT signaling pathways in human keratinocytes in a dose-dependent manner in vitro.
Parameters
Melting point | 197.5°C |
Boiling point | 766.35°C (rough estimate) |
density | 1.0971 (rough estimate) |
refractive index | 1.6500 (estimate) |
storage temp. | 2-8°C |
solubility | methanol: soluble9.80 - 10.20 mg/mL, clear, colorless to faintly yellow |
pka | 12.85±0.70(Predicted) |
form | Solid |
color | Off-White to Pale Beige |
biological source | plant root (Panax ginseng) |
Stability: | Hygroscopic |
InChIKey | GZYPWOGIYAIIPV-VOKNSFSUNA-N |
LogP | 2.900 (est) |
CAS DataBase Reference | 41753-43-9(CAS DataBase Reference) |
Safety Information
Hazard Codes | Xn,Xi,T,F |
Risk Statements | 20/21/22-39/23/24/25-23/24/25-11 |
Safety Statements | 26-36-45-36/37-16-7 |
WGK Germany | 3 |
RTECS | LZ5856000 |
HS Code | 29389090 |
Toxicity | oms-rat-ipr 50 mg/kg CPBTAL 24,2400,76 |
