4-Morpholineethanesulfonic acid CAS#4432-31-9
Excellent Water Solubility: 2-Morpholineethanesulfonic acid offers high solubility in polar solvents such as water, ethanol, methanol, and acetone, enabling convenient formulation and processing.
Outstanding Buffering Performance: The ethanesulfonic acid functional group provides excellent buffering capacity, making it highly suitable for pH-sensitive systems.
High Chemical Stability: Its morpholine ring structure delivers strong stability and chemical inertness, ensuring reliable performance in various applications.
Low Toxicity and Mild Biological Profile: The compound has no obvious toxicity or irritation to organisms, supporting safe use in biological, pharmaceutical, and laboratory environments.
Product Description of 4-Morpholineethanesulfonic Acid CAS#4432-31-9
4-Morpholineethanesulfonic acid appears as a white solid powder under room temperature and standard pressure conditions. It is readily soluble in polar solvents, including water, ethanol, methanol, and acetone, while remaining insoluble in non-polar solvents.
Its molecular structure features both a morpholine ring and an ethanesulfonic acid functional group. The morpholine ring, a nitrogen-containing heterocyclic structure, provides excellent chemical stability and inertness, with no obvious toxicity or biological irritation.
Meanwhile, the ethanesulfonic acid group, as a negatively charged functional moiety, contributes excellent water solubility and strong buffering capacity, making this compound highly suitable for biochemical, pharmaceutical, and laboratory applications.
4-Morpholineethanesulfonic acid Chemical Properties
| Melting point | >300 °C(lit.) |
| Boiling point | 102°C |
| Density | 1.208 (estimate) |
| Refractive index | 1.5500 (estimate) |
| Storage temp. | 2-8°C |
| Solubility | H2O: 0.5 M at 20 °C, clear |
| Form | Powder |
| Pka | pKa at 0.1M ionic: 0°, 6.38; 20°, 6.15; 37°, 5.98; pKa1 1.99; pKa2 6.21; pKa/°C -0.011 |
| Color | White |
| PH | 2.5-4.0 (25℃ in neat) |
| PH Range | 5.5 - 6.7 |
| Water Solubility | 185.2g/L at 20℃ |
| λmax | λ: 260 nm Amax: 0.01 |
| λ: 280 nm Amax: 0.01 | |
| Merck | 135929 |
| BRN | 6350956 |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| InChIKey | SXGZJKUKBWWHRA-UHFFFAOYSA-N |
| LogP | -2.2 at 20℃ |
| CAS DataBase Reference | 4432-31-9(CAS DataBase Reference) |
| EPA Substance Registry System | 4-Morpholineethanesulfonic acid (4432-31-9) |
Safety Information
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36-24/25-22 |
| WGK Germany | 1 |
| RTECS | QE9104530 |
| HS Code | 29349990 |
Product Application of 4-Morpholineethanesulfonic Acid CAS#4432-31-9
This product is widely used as a calcium soap dispersant in soap and toilet soap formulations. It can serve as an effective low-phosphorus or phosphorus-free alternative to sodium tripolyphosphate in detergent systems, and may also be applied as an active ingredient in liquid cleaning formulations.
In industrial applications, it is utilized as a medium-foaming mineral flotation agent. It also functions effectively as a dispersing and wetting agent in leather degreasing, dyes, pigments, and pesticide formulations.
In addition, this product is used as a deinking agent in the printing industry, contributing to improved ink removal performance during paper recycling and processing.




