Pyridoxine hydrochloride CAS#58-56-0
      
                Supports Metabolism: Vitamin B6 is essential for amino acid metabolism and the synthesis of neurotransmitters, supporting overall metabolic functions.
Prevents Deficiency Disorders: It helps prevent conditions like pellagra and treats symptoms of pregnancy-related nausea, radiation-induced vomiting, and toxicity from medications.
Promotes Nervous System Health: Vitamin B6 is vital for maintaining proper nerve function and can aid in alleviating neurological symptoms from deficiencies.
Stable & Versatile: It is stable under normal conditions and dissolves easily in water and ethanol, making it effective in various medicinal formulations.
Vitamin B6, alternatively called pyridoxine or the anti-pellagra vitamin, has the scientific designation 2-methyl-3-hydroxy-4,5-dihydroxymethylpyridine, while its pharmaceutical form is typically pyridoxine hydrochloride. The hydrochloride salt is commonly employed in medicinal preparations. This compound appears as a white or faintly yellow crystalline powder that melts with decomposition at 204-206°C. It dissolves readily in water, ethanol and acetone, but shows only limited solubility in ether. Characterized by an acidic and bitter flavor, it remains stable under normal atmospheric conditions but slowly degrades upon sunlight exposure and tends to sublimate.
When treated with ferric chloride, it yields a reddish-brown coloration. It occurs naturally in various sources including rice bran, vegetables, yeast, molasses and fats, and can be chemically produced from methyl methoxyacetate, acetone and ethyl cyanoacetate. Clinically, it serves to prevent and manage pregnancy-related nausea, radiation-induced vomiting, isoniazid toxicity and gastrointestinal side effects of anticancer medications. Additionally, it finds occasional use as a supplementary therapy for pellagra and certain nutritional deficiency disorders.
| Melting point | 214-215 °C(lit.) | 
| density | 1.2784 (rough estimate) | 
| vapor density | 7.1 (vs air) | 
| refractive index | 1.5800 (estimate) | 
| Fp | 9℃ | 
| storage temp. | room temp | 
| solubility | H2O: 0.1 g/mL at 20 °C, clear, colorless | 
| form | Crystalline Powder | 
| color | White to almost white | 
| PH Range | 3.2 | 
| biological source | synthetic (organic) | 
| Water Solubility | 0.1 g/mL (20 ºC) | 
| Sensitive | Light Sensitive | 
| Merck | 147982 | 
| BRN | 3632435 | 
| BCS Class | 1 | 
| Stability: | Stable. Protect from air and light. | 
| LogP | -1.098 (est) | 
| CAS DataBase Reference | 58-56-0(CAS DataBase Reference) | 
| EPA Substance Registry System | 5-Hydroxy-6-methyl-3,4-pyridinedimethanol, hydrochloride (58-56-0) | 
| Safety Information | |
| Hazard Codes | Xi,T,F | 
| Risk Statements | 36/37/38-39/23/24/25-23/24/25-11 | 
| Safety Statements | 26-37/39-45-36/37-16-7-24/25 | 
| RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution | 
| WGK Germany | 2 | 
| RTECS | UV1350000 | 
| F | 45879 | 
| TSCA | Yes | 
| HS Code | 29362500 | 
| Hazardous Substances Data | 58-56-0(Hazardous Substances Data) | 

 
                                            
                                                                                        
                                         
                                            
                                                                                        
                                         
                                            
                                                                                        
                                         
                                            
                                                                                        
                                         
                                            
                                                                                        
                                        


 
                   
                   
                   
                   
                  