Ethylenediaminetetraacetic acid CAS# 60-00-4
1. Strong Chelating Ability: EDTA can bind to metal ions at six different points, creating highly stable coordination compounds.
2. Effective Ligand: Acts as a potent polydentate ligand, widely used in industrial and laboratory applications for metal ion complexation.
3. Wide Application Range: Utilized in water treatment, pharmaceuticals, agriculture, and as an additive in various chemical processes.
4. Chemical Stability: Stable under high temperatures (up to 250°C) and resistant to decomposition, making it suitable for demanding environments.
Ethylenediaminetetraacetic Acid (EDTA) serves as a widely used polydentate ligand. In aqueous solution, EDTA readily loses its hydrogen atoms to form the EDTA4- anion. This anionic species possesses six potential coordination sites - two nitrogen atoms and four oxygen atoms - that can simultaneously bind to a metal ion.
When EDTA complexes with a metal ion, it envelops the metal center through all six binding sites, creating an exceptionally stable coordination compound. The firm attachment of EDTA to the metal ion resembles the powerful grip of a crab or lobster's claw, which explains the origin of the term "chelation." EDTA's remarkable effectiveness as a chelating agent stems from its ability to coordinate with a metal ion through as many as six different points simultaneously.
Ethylenediaminetetraacetic acid Chemical Properties |
Melting point | 250 °C (dec.) (lit.) |
Boiling point | 434.18°C (rough estimate) |
bulk density | 600kg/m3 |
density | 1.46 g/cm3 at 20 °C |
vapor pressure | <0.013 hPa (20 °C) |
refractive index | n20/D 1.363 |
Fp | >400°C DIN 51758 |
storage temp. | 2-8°C |
solubility | 3 M NaOH: 100 mg/mL |
form | crystalline |
pka | pKa 2 (Uncertain);10.26 (Uncertain) |
color | White to almost white |
PH | 2.5 (10g/l, H2O, 23℃)(slurry) |
Odor | Odorless |
PH Range | 2.5 at 10 g/l at 23 °C |
Water Solubility | 0.5 g/L (25 ºC) |
λmax | λ: 280 nm Amax: ≤0.25 |
Decomposition | 240 °C |
Merck | 14,3517 |
BRN | 1716295 |
Stability: | Stable. Incompatible with copper, copper alloys, nickel, aluminium, strong oxidizing agents, strong bases |
LogP | -0.836 (est) |
CAS DataBase Reference | 60-00-4(CAS DataBase Reference) |
NIST Chemistry Reference | N,N'-1,2-Ethane diylbis-(N-(carboxymethyl)glycine)(60-00-4) |
EPA Substance Registry System | Ethylenediaminetetraacetic acid (60-00-4) |
Safety Information |
Hazard Codes | Xi |
Risk Statements | 36-52/53-36/37/38-36/38 |
Safety Statements | 26-61-37/39-36 |
RIDADR | UN 3077 9 / PGIII |
WGK Germany | 2 |
RTECS | AH4025000 |
F | 3 |
Autoignition Temperature | >200 °C |
TSCA | Yes |
HS Code | 2922 49 85 |
Hazardous Substances Data | 60-00-4(Hazardous Substances Data) |
Toxicity | LD50 orally in Rabbit: 2580 mg/kg |
