2-Phenoxyethanol CAS# 122-99-6

  1. Effective Preservative: Phenoxyethanol has strong antimicrobial properties, inhibiting bacteria, yeast, and mold growth, making it an essential preservative in cosmetics and personal care products.

  2. Safe for Skin: With low toxicity and minimal irritation, phenoxyethanol is well-suited for both topical and injectable formulations, offering safety and ease of absorption through the skin.

  3. Safer Alternative: As a preservative, phenoxyethanol is considered a safer alternative to parabens, which have raised concerns about potential endocrine disruption, making it a preferred choice.

  4. Versatile Usage: In addition to its cosmetic applications, phenoxyethanol is used in pharmaceuticals and vaccines to extend shelf life and prevent contamination, highlighting its broad utility.


Product Details

Phenoxyethanol is an organic chemical compound, classified as a glycol ether, commonly found in a variety of dermatological and cosmetic products, including skin creams, lotions, and sunscreens. This colorless, oily liquid has antimicrobial properties and is often used as a preservative in cosmetics and personal care items due to its ability to inhibit the growth of bacteria, yeast, and mold. Typically, it is used in conjunction with quaternary ammonium compounds to enhance its bactericidal activity.


2-Phenoxyethanol CAS# 122-99-6


In addition to its widespread use in cosmetics, phenoxyethanol is also found in vaccines and pharmaceuticals as a preservative to prevent contamination and extend shelf life. Its low toxicity and ability to be absorbed by the skin without causing significant irritation make it a popular choice for both topical and injectable products. Furthermore, it is often considered a safer alternative to other preservatives, such as parabens, which have raised concerns over potential endocrine disruption. Despite its benefits, phenoxyethanol is regulated in certain regions, and its use is limited to specific concentrations, typically not exceeding 1% in cosmetic products.


2-Phenoxyethanol CAS# 122-99-6


2-Phenoxyethanol Chemical Properties

 

Melting point 

11-13 °C (lit.)


Boiling point 

247 °C (lit.)


density 

1.102 g/mL at 25 °C (lit.)


vapor density 

4.8 (vs air)


vapor pressure 

0.01 mm Hg ( 20 °C)


refractive index 

n20/D 1.539


FEMA 

4620 | 2-PHENOXYETHANOL


Fp 

>230 °F


storage temp. 

Store below +30°C.


solubility 

soluble, clear, colorless to very faintly yellow


pka

14.36±0.10(Predicted)


form 

Liquid


color 

Clear colorless


Specific Gravity

1.109 (20/4℃)


Odor

Faint aromatic odor


PH Range

7 at 10 g/l at 23 °C


PH

7 (10g/l, H2O, 23℃)


explosive limit

1.4-9.0%(V)


Odor Type

floral


Water Solubility 

30 g/L (20 ºC)


Merck 

14,7257


BRN 

1364011


InChIKey

QCDWFXQBSFUVSP-UHFFFAOYSA-N


LogP

1.2 at 23℃


CAS DataBase Reference

122-99-6(CAS DataBase Reference)


NIST Chemistry Reference

2-Phenoxyethanol(122-99-6)


EPA Substance Registry System

Ethylene glycol monophenyl ether (122-99-6)


Safety Information


Hazard Codes 

Xn,Xi

Risk Statements 

22-36-R36-R22

Safety Statements 

26-S26

WGK Germany 

1

RTECS 

KM0350000

Autoignition Temperature

535 °C DIN 51794

Hazard Note 

Irritant

TSCA 

Yes

HS Code 

29094990

Hazardous Substances Data

122-99-6(Hazardous Substances Data)

Toxicity

LD50 orally in Rabbit: 1850 mg/kg LD50 dermal Rabbit > 2000 mg/kg


2-Phenoxyethanol CAS# 122-99-6

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