1-Ethyl-2-pyrrolidone CAS#2687-91-4
Excellent Solvent Performance: N-Ethyl-2-pyrrolidone provides strong solvency, low volatility, and a low dielectric constant, making it suitable for use as an efficient aprotic solvent in various chemical processes.
Enhanced Transdermal Absorption: It acts as an effective penetration enhancer, improving transdermal absorption by interacting with the multilamellar liposome structure of stratum corneum lipids.
Versatility in Industrial Applications: The compound serves multiple roles—such as an intermediate for polycarboxylic acid synthesis and a solvent with stable performance under low light and constant pressure conditions.
Low Vapor Pressure for Safe Handling: Its low vapor pressure reduces evaporative loss, contributing to safer handling in controlled environments and minimizing emissions during use.
Products Description of Potassium phosphate CAS#778-53-2
1-Ethyl-2-pyrrolidone is known as a compound that enhances transdermal absorption, and its influence on the multilamellar liposomes of stratum corneum lipids has been investigated.
N-Ethyl-2-pyrrolidone is widely used as a solvent. Its low boiling point makes it suitable for applications under low-light conditions and constant pressure. It also serves as an intermediate in synthesizing polycarboxylic acids and participates in processes related to viscosity and hydrogen bonding.
N-Ethyl-2-pyrrolidone (NEP) is a clear, colorless liquid functioning as a low-volatility aprotic solvent that is classified as a reproductive toxicant. It features strong solvency, low vapor pressure, and a low dielectric constant.
Neurotoxin – Associated with Acute Solvent Syndrome.
Occupational hepatotoxin – Identified as a secondary hepatotoxin, with potential toxic effects observed in workplace exposure or animal studies involving ingestion or experimental poisoning.
Reproductive toxicant – A substance harmful to the reproductive system, capable of causing developmental issues or impairing reproductive function in males or females.
1-Ethyl-2-pyrrolidone Chemical Properties
Melting point | 87.5-88.5 °C |
Boiling point | 97 °C/20 mmHg (lit.) |
Density | 0.992 g/mL at 25 °C (lit.) |
Vapor pressure | 18Pa at 20℃ |
Refractive index | n |
Fp | 169 °F |
Storage temp. | Sealed in dry,Room Temperature |
Pka | -0.41±0.20(Predicted) |
Form | Liquid |
Color | Clear |
PH | 8-9 (100g/l, H2O, 20℃) |
Explosive limit | 1.3-7.7%(V) |
Water Solubility | 1000g/L at 23℃ |
BRN | 107971 |
InChIKey | ZFPGARUNNKGOBB-UHFFFAOYSA-N |
LogP | -0.2 at 20℃ |
CAS DataBase Reference | 2687-91-4(CAS DataBase Reference) |
NIST Chemistry Reference | 1-Ethyl-2-pyrrolidinone(2687-91-4) |
EPA Substance Registry System | 2-Pyrrolidinone, 1-ethyl- (2687-91-4) |
Safety Information
Hazard Codes | Xn,T |
Risk Statements | 22-36-62-41-61 |
Safety Statements | 26-36-45-36/37/39-53 |
WGK Germany | 1 |
RTECS | UY5769250 |
TSCA | Yes |
HS Code | 29337900 |
