Chlorogenic acid CAS#327-97-9
Neuroprotective Effects: Chlorogenic acid (CGA) is known for its strong neuroprotective properties, helping to support brain health.
Antioxidant and Antitumor Properties: It exhibits significant antioxidant and antitumor effects, making it valuable for health maintenance and disease prevention.
Metabolism Regulation: CGA is beneficial in regulating glucose and lipid metabolism, potentially aiding in the prevention of metabolic disorders like type 2 diabetes and obesity.
Anti-inflammatory Benefits: It modulates inflammatory responses and protects against oxidative stress, supporting its use in nutraceuticals and functional foods.
Chlorogenic acid (CGA) is a naturally occurring polyphenolic compound widely distributed in various plants, with especially high concentrations in coffee beans. It is recognized for its broad spectrum of biological activities, including strong neuroprotective effects, as well as significant antiviral, antifungal, antioxidant, and antitumor properties.
Recent studies also suggest that CGA may play an important role in regulating glucose and lipid metabolism, enhancing insulin sensitivity, and potentially aiding in the prevention of metabolic disorders such as type 2 diabetes and obesity. In addition, its ability to modulate inflammatory responses and protect against oxidative stress further supports its potential applications in nutraceuticals and functional foods.
Parameters
Melting point | 210 °C (dec.) (lit.) |
alpha | -36 º (c=1, H2O) |
Boiling point | 407.55°C (rough estimate) |
density | 1.3594 (rough estimate) |
refractive index | -37 ° (C=1, H2O) |
storage temp. | 2-8°C |
solubility | Soluble in ethanol and acetone. |
pka | 3.91±0.50(Predicted) |
form | Powder, Crystals, Needles and/or Chunks |
color | White to almost white |
Water Solubility | SOLUBLE IN HOT WATER |
Merck | 14,2142 |
InChIKey | CWVRJTMFETXNAD-JUHZACGLSA-N |
LogP | -0.356 (est) |
CAS DataBase Reference | 327-97-9(CAS DataBase Reference) |
EPA Substance Registry System | Chlorogenic acid (327-97-9) |
Safety Information
Hazard Codes | Xi |
Risk Statements | 68 |
Safety Statements | 24/25 |
WGK Germany | 3 |
RTECS | GU8480000 |
Hazard Note | Irritant |
HS Code | 29182900 |
Toxicity | LDLo intraperitoneal in rat: 4gm/kg |
