L-Leucine CAS#61-90-5
Essential Amino Acid: L-leucine is one of the eight essential amino acids, playing a crucial role in protein synthesis and overall health.
Branched-Chain Amino Acid: Along with L-isoleucine and L-valine, L-leucine is part of the three branched-chain amino acids (BCAAs), important for muscle repair and energy production.
Proteins Component: L-leucine is integral to the structure of many proteins, supporting various biological functions.
Enantiomeric Forms: L-leucine and D-leucine are enantiomers, providing versatility in biochemical applications.
L-leucine is one of the eight essential amino acids and is classified as an aliphatic amino acid, found in various proteins. Together with L-isoleucine and L-valine, L-leucine forms the group of branched-chain amino acids (BCAAs). L-leucine and D-leucine are enantiomers of each other.
L-Leucine Chemical Properties
Melting point | >300 °C (lit.) |
alpha | 15.4 º (c=4, 6N HCl) |
Boiling point | 122-134 °C(Press: 2-3 Torr) |
bulk density | 300-400kg/m3 |
density | 1,293 g/cm3 |
vapor pressure | <1 hPa (20 °C) |
refractive index | 1.4630 (estimate) |
FEMA | 3297 | L-LEUCINE |
Fp | 145-148°C |
storage temp. | 2-8°C |
solubility | 1 M HCl: 50 mg/mL |
form | |
pka | 2.328(at 25℃) |
color | White to Off-white |
Odor | at 100.00?%. odorless |
PH | 5.5-6.5 (20g/l, H2O, 20℃) |
biological source | plant |
Optical Rotation | [α]20/D +15.5°, c = 2 in 6 M HCl |
Water Solubility | 22.4 g/L (20 C) |
λmax | λ: 260 nm Amax: 0.05 |
JECFA Number | 1423 |
Sublimation | 145-148 ºC |
Merck | 14,5451 |
BRN | 1721722 |
Stability: | Stability Moisture and light sensitive. Incompatible with strong oxidising agents. |
LogP | 0.80 |
CAS DataBase Reference | 61-90-5(CAS DataBase Reference) |
NIST Chemistry Reference | Leucine(61-90-5) |
EPA Substance Registry System | L-Leucine (61-90-5) |
Safety Information
Safety Statements | 24/25 |
WGK Germany | 3 |
RTECS | OH2850000 |
TSCA | Yes |
HS Code | 29224995 |
Hazardous Substances Data | 61-90-5(Hazardous Substances Data) |
Amino acid-based drugs are used in amino acid infusions and comprehensive amino acid formulations. They are utilized for diagnosing and treating conditions in children such as idiopathic high blood sugar and glucose metabolism disorders, bile liver disease with reduced secretion, anemia, poisoning, muscular dystrophy, poliomyelitis, neuritis, and mental health disorders.
