Dimethyl Sulfoxide CAS#67-68-5
Versatile Solvent: Dimethyl sulfoxide (DMSO) is an effective polar aprotic solvent capable of dissolving both polar and nonpolar compounds, making it highly versatile for various applications.
High Miscibility: It is miscible with a broad range of organic solvents and water, enhancing its compatibility in different environments and processes.
Efficient in Various Applications: Suitable for industrial, chemical, and pharmaceutical uses.
Established History: Synthesized in 1866, DMSO has a long history of use in various chemical and industrial fields, proving its reliability and effectiveness over time.
Dimethyl sulfoxide, an organosulfur compound, was first synthesized in 1866 by Alexander Zaytsev in the Russian Empire. This colorless liquid is a crucial polar aprotic solvent, capable of dissolving both polar and nonpolar substances. It is miscible with a variety of organic solvents and water.
Dimethyl sulfoxide Chemical Properties
Melting point | 18.4 °C |
Boiling point | 189 °C(lit.) |
density | 1.100 g/mL at 20 °C |
vapor density | 2.7 (vs air) |
vapor pressure | 0.42 mm Hg ( 20 °C) |
refractive index | n20/D 1.479(lit.) |
FEMA | 3875 | METHYLSULFINYLMETHANE |
Fp | 192 °F |
storage temp. | Store at +5°C to +30°C. |
solubility | H2O: miscible (completely) |
pka | 35(at 25℃) |
form | liquid (temperature dependent) |
color | clear colorless |
Relative polarity | 0.444 |
Odor | Mild garlic odor |
Odor Type | alliaceous |
biological source | synthetic |
explosive limit | 1.8-63.0%(V) |
Water Solubility | Soluble in water, methanol, acetone, ether, benzene, chloroform. |
FreezingPoint | 18.4℃ |
Sensitive | Hygroscopic |
λmax | λ: 285 nm Amax: ≤0.20 |
JECFA Number | 507 |
Merck | 14,3259 |
BRN | 506008 |
Dielectric constant | 41.9（55℃） |
Stability | Stable. Incompatible with a very wide range of materials, including acid chlorides, strong acids, strong oxidizing agents, strong reducing agents, phosphorus halides, moisture, copper wool + trichloroacetic acid. Reacts violently with a number of materials - consult a full data sheet before use. Hygroscopic. |
InChIKey | IAZDPXIOMUYVGZ-UHFFFAOYSA-N |
LogP | -1.35 |
Surface tension | 42.179mN/m at 298.15K |
CAS DataBase Reference | 67-68-5(CAS DataBase Reference) |
NIST Chemistry Reference | Dimethyl sulfoxide(67-68-5) |
EPA Substance Registry System | Dimethyl sulfoxide (67-68-5) |
Absorption | passes test |
DMSO is a polar aprotic solvent utilized in chemical reactions, polymerase chain reactions (PCR), and as a cryoprotectant for vitrification in the preservation of cells, tissues, and organs. It helps prevent mechanical damage to cells caused by ice crystal formation during freezing. DMSO is commonly used in the storage of primary, sub-cultured, and recombinant heteroploid and hybridoma cell lines, as well as embryonic stem cells (ESC) and hematopoietic stem cells. It is often combined with BSA or fetal bovine serum (FBS) in these applications.
