6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride CAS#2328-12-3

  • Valuable Pharmaceutical Intermediate: 6,7-Dimethoxy-1,2,3,4-Tetrahydroisoquinoline hydrochloride is widely used as an important intermediate in pharmaceutical synthesis.

  • High Purity Physical Form: It is available as white to slightly beige glossy flakes or crystalline powder, providing excellent suitability for research and manufacturing applications.

  • Excellent Solubility in Polar Solvents: The compound is readily soluble in water and methanol and can achieve concentrations of up to 25 mg/mL in a methanolic 1N NaOH solution.

  • Well-Defined Chemical Properties: With a melting point of 260–265°C and characterized solubility behavior, it offers reliable performance in laboratory and chemical synthesis processes.


Product Details

Products Description of 6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride CAS#2328-12-3
6,7-Dimethoxy-1,2,3,4-Tetrahydroisoquinoline hydrochloride (CAS#2328-12-3) is an isoquinoline-based organic compound and a plant-derived alkaloid, naturally found in the cactus Backebergia militaris. It appears as white to slightly beige glossy flakes or crystalline powder and is mainly used as a pharmaceutical synthesis intermediate. The compound has a melting point of 260–265 °C. It is soluble in a 1N NaOH methanol solution, reaching concentrations up to 25 mg/mL (forming a clear, colorless solution), readily dissolves in polar solvents such as water and methanol, and is only sparingly soluble in non-polar solvents like ether and petroleum ether.

6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride CAS#2328-12-3

6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride Chemical Properties

Melting point 260-265 °C(lit.)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility soluble25mg/mL, clear, colorless (1N NaOH in methanol)
form Shiny Flakes or Crystalline Powder
color White to slightly beige
BRN 3634126
InChIKeySHOWAGCIRTUYNA-UHFFFAOYSA-N
CAS DataBase Reference2328-12-3(CAS DataBase Reference)
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
RTECS NX5017980
HazardClass IRRITANT
HS Code 29334900
Toxicitymouse,LD50,intraperitoneal,272mg/kg (272mg/kg),BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLDBEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY),Yakugaku Zasshi. Journal of Pharmacy. Vol. 88, Pg. 1197, 1968.

6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride CAS#2328-12-3

Product Application of 6,7-Dimethoxy-1,2,3,4-Tetrahydroisoquinoline Hydrochloride CAS#2328-12-3

It serves as a starting material for the synthesis of more complex isoquinoline and quinolizidine derivatives.

6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride CAS#2328-12-3

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