2-Dimethylaminoisopropyl chloride hydrochloride CAS#4584-49-0
Provides excellent chemical stability and consistent quality, ensuring reliable performance in a wide range of organic synthesis applications.
Acts as a valuable pharmaceutical intermediate for the synthesis of lipophilic chalcone analogues with high reaction efficiency.
Widely applied in the research and development of antitubercular compounds, supporting advanced drug discovery projects.
Features strong reactivity and broad compatibility with synthetic routes, helping improve process efficiency and product yield.
Product Description of 2-Dimethylaminoisopropyl Chloride Hydrochloride CAS#4584-49-0
2-Dimethylaminoisopropyl chloride hydrochloride is the hydrochloride form of 2-Dimethylaminoisopropyl Chloride, mainly used in the synthesis of lipophilic chalcone analogues with antitubercular activity.
2-Dimethylaminoisopropyl chloride hydrochloride Chemical Properties
| Melting point | 187-190 °C(lit.) |
| storage temp | Store below +30°C. |
| solubility | 2000g/l |
| form | Crystalline Powder |
| color | White to light cream |
| PH | 5-6 (500g/l, H2O, 20℃) |
| Water Solubility | 2000 g/L (20 º C) |
| Sensitive | Hygroscopic |
| BRN | 3670215 |
| InChI | InChI=1S/C5H12ClN.ClH/c1-5(6)4-7(2)3;/h5H,4H2,1-3H3;1H |
| InChIKey | OCWGRWAYARCRTQ-UHFFFAOYSA-N |
| SMILES | C(Cl)(C)CN(C)C.Cl |
| CAS DataBase Reference | 4584-49-0(CAS DataBase Reference) |
| EPA Substance Registry System | 2-Chloro-N,N-dimethyl-1-propanamine hydrochloride (4584-49-0) |
Safety Information
| Hazard Codes | Xn,Xi |
| Risk Statements | 22-36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | 2811 |
| WGK Germany | 3 |
| RTECS | TY1225000 |
| TSCA | Yes |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| HS Code | 29211980 |
Primary Applications
This compound is a key building block for several medications:
Antipsychotics: Synthesis of Chlorpromazine
Antihistamines: Synthesis of Promethazine (Phenergan) and Isothipendyl
Opioids: Intermediate for Methadone production
Antidepressants: Synthesis of Doxepin hydrochloride
Other: Used in the creation of methaqualone and lipophilic chalcones for antitubercular research
