1,2-O-Isopropylidene-Alpha-DXylofuranose CAS#20031-21-4
Key Chiral Intermediate: Serves as an important chiral building block in the synthesis of atorvastatin side chains and other pharmaceutical compounds.
High Synthetic Value: Can be converted into 3-deoxy-1,2-O-isopropylidene-D-xylofuranose, enabling further complex molecule construction.
Supports Drug Development: Plays a critical role in the preparation of multiple drug intermediates, enhancing its relevance in pharmaceutical research.
Versatile Chemical Application: Applicable in various organic synthesis pathways, making it useful for developing diverse bioactive molecules.
Product Description of 1,2-O-Isopropylidene-α-D-Xylofuranose (CAS No. 20031-21-4)
1,2-O-Isopropylidene-α-D-xylofuranose can be used as a precursor for the synthesis of 3-deoxy-1,2-O-isopropylidene-D-xylofuranose. This compound serves as a chiral intermediate in the preparation of the pharmacologically active side chain of atorvastatin. It also plays a key role in the synthesis of various other pharmaceutical intermediates.
1,2-O-Isopropylidene-Alpha-D-Xylofuranose Chemical Properties
| Melting point | 69-71 °C(lit.) |
| Boiling point | 112-114 °C0.06 mm Hg(lit.) |
| Alpha | -19.2 º (C=1 IN H2O) |
| Density | 1.2422 (rough estimate) |
| Refractive index | -19 ° (C=1, H2O) |
| Storage temp | Keep in dark place,Sealed in dry,Room Temperature |
| Solubility | Methanol (Slightly), Water (Slightly) |
| Pka | 13.23±0.60(Predicted) |
| Form | Waxy Solid or Coarse Crystals and Chunks |
| Color | White to Off-white |
| Optical activity | [α]25/D 19.2°, c = 1 in H2O |
| BRN | 81520 |
| InChIKey | JAUQZVBVVJJRKM-VZFHVOOUSA-N |
| CAS DataBase Reference | 20031-21-4(CAS DataBase Reference) |
| EPA Substance Registry System | .alpha.-D-Xylofuranose, 1,2-O-(1-methylethylidene)- (20031-21-4) |
| Safety Statements | 22-24/25 |
| WGK Germany | 3 |
| F | 10 |
| HS Code | 29321900 |
