4-Fluorobenzaldehyde CAS#459-57-4
Versatile Organic Intermediate: 4-Fluorobenzaldehyde (CAS#459-57-4) is a crucial synthetic intermediate widely used in organic chemistry.
Distinct Reactivity: The presence of fluorine atoms imparts unique reactivity, making it an important reactive site in organic synthesis.
Chemical Versatility: It exhibits typical aldehyde group characteristics, enabling it to undergo a variety of chemical reactions, such as oxidation, reduction, and condensation.
Aromatic Compound: This compound is a colorless to pale yellow liquid with a distinct aromatic smell, adding value in fragrance and other specialty applications.
4-Fluorobenzaldehyde (CAS#459-57-4) is a key organic synthetic intermediate. It typically appears as a colorless to pale yellow liquid with a distinct aromatic odor. Exhibiting the classic chemical characteristics of an aldehyde group, it is capable of undergoing reactions like oxidation, reduction, and condensation. The fluorine atoms present in its structure contribute unique reactivity, making it a valuable reactive site for various organic synthesis processes.
Parameters
Melting point | -10 °C (lit.) |
Boiling point | 181 °C/758 mmHg (lit.) |
density | 1.157 g/mL at 25 °C (lit.) |
vapor pressure | 19 hPa (70 °C) |
refractive index | n |
Fp | 134 °F |
storage temp. | Store below +30°C. |
solubility | Chloroform, Methanol |
form | Liquid |
color | Clear colorless to yellow |
Specific Gravity | 1.157 |
Water Solubility | IMMISCIBLE |
Sensitive | Air Sensitive |
BRN | 385857 |
Stability: | Air Sensitive |
InChIKey | UOQXIWFBQSVDPP-UHFFFAOYSA-N |
CAS DataBase Reference | 459-57-4(CAS DataBase Reference) |
NIST Chemistry Reference | Benzaldehyde, 4-fluoro-(459-57-4) |
EPA Substance Registry System | Benzaldehyde, 4-fluoro- (459-57-4) |
Safety Information
Hazard Codes | Xi,F |
Risk Statements | 36/37/38 |
Safety Statements | 26-36-37/39-36/37/39-27 |
RIDADR | UN 1989 3/PG 3 |
WGK Germany | 2 |
F | 9-23 |
Hazard Note | Flammable |
TSCA | T |
HazardClass | 3.2 |
PackingGroup | III |
HS Code | 29130000 |
4-Fluorobenzaldehyde is a fluorinated derivative of benzaldehyde known for its inhibitory effect on mushroom tyrosinase. It is utilized in the synthesis of pyrazolopyridine derivatives, which are used as mitogen-activated protein kinase (MAPK) inhibitors. Additionally, it serves as an important intermediate in the synthesis of various pharmaceutical compounds.
